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Zai Lab (ZLAB) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Zai Lab
NasdaqGM•Healthcare•Biotechnology
$24.67-0.13(-0.01%)Pre-market
Market Cap
$27.56B
P/S
62.1x
P/B
45.4x

Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases. Its commercial products include Zejula, an orally administered poly (ADP-ribose) polymerase 1/2 inhibitor for treating ovarian cancer; VYVGART, a human IgG1 antibody fragment for generalized myasthenia gravis and chronic inflammatory demyelinating polyneuropathy; NUZYRA for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections; Optune for glioblastoma multiforme; Qinlock for gastrointestinal stromal tumors; Xacduro for treating hospital-acquired and ventilator-associated bacterial pneumonia caused by a cinetobacter baumannii-calcoaceticus complex; and Augtyro for the treatment of ROS proto-oncogene 1 and non-small cell lung cancer. The company has a strategic collaboration with Tesaro, Inc., NovoCure Ltd., Deciphera Pharmaceuticals, LLC, Paratek Bermuda Ltd., argent BV, Turning Point Therapeutics, Inc., Entasis Therapeutics Holdings Inc., Karuna Therapeutics, Inc., Pfizer Inc., Amgen Inc., and with Boehringer Ingelheim GmbH. The company was incorporated in 2013 and is based in Pudong, China.

D

How this company scores

WeakMetricSide Score: 46/100

Grade capped at D — Interest coverage below 1× (-41.6x) — earnings cannot cover interest. Strongest: Profitability (17/25); weakest: Balance Sheet & Red Flags (7/25).

Profitability17/25
Growth14/25
Balance Sheet & Red Flags7/25
Cash & Earnings Quality8/25
Strengths
Long cash runwayProfit converts from growthConsistent growthNet cash position
Grade capped at D
  • Interest coverage below 1× (-41.6x) — earnings cannot cover interest.

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/S · 62.1x5y range 42.7x – 681.8x
P/S 62.1x · below its 20-quarter median

Currently below its 20-quarter median.

P/B · 45.4x5y range 21.3x – 64.0x
P/B 45.4x · above its 20-quarter median

Currently above its 20-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $27.56B

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$443.75M
2Q
Q. Revenue
$105.75M
3%
TTM EBITDA
$-248.17M
3Q
TTM Op. Income
$-264.10M
3Q
Q. Op. Income
$-76.49M
39%
TTM Net Income
$-188.21M
2Q
Q. Net Income
$-50.83M
25%
EPS
$-0.05
25%
Shares Out.
$1.12B
7Q
$443.75M in TTM revenue grew 4.4% YoY, reaching $105.75M last quarter. TTM EBITDA of $-248.17M and TTM operating income of $-264.10M show growth is flowing through to the bottom line. However, net income is negative at $188.21M — growth is not yet reaching the bottom line. Across the last 8 quarters, TTM revenue has fallen for 2 consecutive quarters — a weakening trend.

Margins

Gross, EBITDA, operating, and net margin trends

Gross Margin
54.5%
10%
EBITDA Margin
-68.4%
46%
Op. Margin
-72.3%
44%
Net Margin
-48.1%
29%
Op. margin of -72.3% is down 22.0% YoY — costs are rising relative to revenue. Net margin at -48.1% and gross margin of 54.5% show how much of each revenue dollar survives to profit. Over the past year, operating margin is down 44% — an improving trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
62.1x
2Q
P/B Ratio
45.4x
2Q
P/S of 62.1x and P/B of 45.4x. P/S is high, meaning growth expectations are priced in.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$1.07B
2Q
Cash
$607.52M
5Q
Long-Term Debt
N/A
Book Value
$607.04M
6Q
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-63.41M
104%
TTM Free Cash Flow
$-139.57M
24%
FCF Margin
-31.5%
27%
FCF / Net Income
0.7
14%
TTM FCF of $-139.57M on $-63.41M in operating cash flow. The FCF / Net Income ratio of 0.7x means free cash flow covers net income — earnings are backed by cash. Over the past year, free cash flow is up 24% — a weakening trend.

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Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 13.8% — significant dilution, likely from stock compensation or capital raises.