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Shattuck Labs (STTK) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Shattuck Labs
NasdaqGS•Healthcare•Biotechnology
$6.79-0.17(-0.02%)Market closed
Market Cap
$804.63M
P/S
804.6x
P/B
3.8x

Shattuck Labs, Inc., a clinical-stage biotechnology company, engages in the development of antibodies for the treatment of inflammatory and immune-mediated diseases in the United States. The company develops SL-325, a death receptor 3 blocking monoclonal antibody, which is in Phase I clinical trial for the treatment of tumor necrosis factor like ligand 1A; and SL-425, a half-life extended version of SL-325, which is under IND-enabling chronic good laboratory practices toxicity study. It is also involved in the development of various preclinical DR3-based bispecific antibodies for the treatment of patients with inflammatory bowel disease or other immune-mediated indications; and TRIM7, an oncology-focused program. The company was incorporated in 2016 and is headquartered in Austin, Texas.

C

How this company scores

AverageMetricSide Score: 41/100

Strongest: Balance Sheet & Red Flags (15/25); weakest: Growth (6/25).

Profitability12/25
Growth6/25
Balance Sheet & Red Flags15/25
Cash & Earnings Quality8/25
Strengths
Interest easily coveredProfit converts from growthNet cash position

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/S · 804.6x5y range 3.9x – 804.6x
P/S 804.6x · above its 20-quarter median

Currently above its 20-quarter median.

P/B · 3.8x5y range 0.6x – 7.0x
P/B 3.8x · above its 20-quarter median

Currently above its 20-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $804.63M

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$1.00M
67%
Q. Revenue
$0
TTM EBITDA
$-50.36M
2Q
TTM Op. Income
$-55.79M
2Q
Q. Op. Income
$-16.16M
3Q
TTM Net Income
$-52.57M
2Q
Q. Net Income
$-15.15M
3Q
EPS
$-0.12
2Q
Shares Out.
$129.78M
2Q
$1.00M in TTM revenue declined 66.6% YoY, reaching $0 last quarter. TTM EBITDA of $-50.36M and TTM operating income of $-55.79M show growth is flowing through to the bottom line. However, net income is negative at $52.57M — growth is not yet reaching the bottom line. Over the past year, TTM revenue is down 67% — a steady trend.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-1615500000.0%
3Q
Net Margin
-1515200000.0%
3Q
Op. margin of -1615500000.0% is down 312300000.0% YoY — costs are rising relative to revenue. Net margin at -1515200000.0% Across the last 8 quarters, operating margin has fallen for 3 consecutive quarters — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
804.6x
6Q
P/B Ratio
3.8x
438%
P/S of 804.6x and P/B of 3.8x. P/S is high, meaning growth expectations are priced in.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$220.67M
2Q
Cash
$63.30M
25%
Long-Term Debt
N/A
Book Value
$211.14M
2Q
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-10.19M
2%
TTM Free Cash Flow
$-41.24M
26%
FCF Margin
-4124.0%
121%
FCF / Net Income
0.8
14%
TTM FCF of $-41.24M on $-10.19M in operating cash flow. The FCF / Net Income ratio of 0.8x means free cash flow covers net income — earnings are backed by cash. Over the past year, free cash flow is up 26% — an improving trend.

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Revenue Decline

Red Flag

TTM revenue has contracted 79.8% — significant decline indicating deteriorating demand.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 155.3% — significant dilution, likely from stock compensation or capital raises.