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Replimune Group (REPL) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Replimune Group
NasdaqGS•Healthcare•Biotechnology
$14.77-0.27(-0.02%)Pre-market
Market Cap
$1.25B
P/B
11.8x

Replimune Group, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of oncolytic immunotherapies to treat cancer in the United States and the United Kingdom. The company's proprietary oncolytic immunotherapy product candidates are designed and intended to activate the immune system against cancer. Its lead product candidate is RP1, a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF for a range of solid tumors. The company is also developing RP2 that expresses an anti-CTLA-4 antibody-like protein to block the inhibition of the immune response otherwise caused by CTLA-4. The company was founded in 2015 and is headquartered in Woburn, Massachusetts.

D

How this company scores

WeakMetricSide Score: 33/100

Strongest: Balance Sheet & Red Flags (14/25); weakest: Cash & Earnings Quality (6/25).

Profitability7/25
Growth6/25
Balance Sheet & Red Flags14/25
Cash & Earnings Quality6/25
Strengths
Net cash positionImproving margins

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/B · 11.8x5y range 1.3x – 11.8x
P/B 11.8x · above its 20-quarter median

Currently above its 20-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $1.25B

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-294.35M
2Q
TTM Op. Income
$-297.74M
2Q
Q. Op. Income
$-68.25M
25%
TTM Net Income
$-297.01M
2Q
Q. Net Income
$-69.77M
20%
EPS
$-0.72
5Q
Shares Out.
$96.86M
5Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-294.35M and TTM operating income of $-297.74M show growth is flowing through to the bottom line. However, net income is negative at $297.01M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-6824700000.0%
25%
Net Margin
-6976600000.0%
20%
Op. margin of -6824700000.0% is up 2217500000.0% YoY — cost efficiency is improving. Net margin at -6976600000.0% Over the past year, operating margin is up 25% — an improving trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
P/B Ratio
11.8x
367%
P/S of 0.0x and P/B of 11.8x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$252.45M
6Q
Cash
$185.36M
90%
Long-Term Debt
$84.11M
7Q
Book Value
$105.64M
6Q
D/E Ratio
0.8
6Q
Debt/EBITDA
N/A
With $252.45M in assets and $84.11M in long-term debt, D/E is 0.8and book value is $105.64M — a conservative capital structure with a cushion to weather downturns. Across the last 8 quarters, debt/equity has risen for 6 consecutive quarters — a weakening trend.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-75.73M
2%
TTM Free Cash Flow
$-280.55M
23%
FCF Margin
N/A
FCF / Net Income
0.9
5Q
TTM FCF of $-280.55M on $-75.73M in operating cash flow. The FCF / Net Income ratio of 0.9x means free cash flow covers net income — earnings are backed by cash. Over the past year, free cash flow is down 23% — an improving trend.

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Leverage Risk

Watch

Debt-to-equity has risen 472.9% recently — increasing financial risk even if the current ratio is manageable.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 23.3% — significant dilution, likely from stock compensation or capital raises.