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Pulse Biosciences (PLSE) Stock Fundamentals, Analysis & Risk Signals

Health score, competitive moat, risk signals, and key metrics at a glance.

NasdaqCM•Healthcare•Medical Instruments & Supplies
D
WeakMetricSide Score: 39/100
ProfitabilityProfit9/25
GrowthGrowth9/25
Balance Sheet & Red FlagsBalance15/25
Cash & Earnings QualityCash6/25

Strongest: Balance Sheet & Red Flags (15/25); weakest: Cash & Earnings Quality (6/25).

Price & Volume
Market Cap $2.57B

Pulse Biosciences, Inc. operates as a novel bioelectric medicine company. It offers nPulse System, a novel Nanosecond Pulsed-Field Ablation delivery platform to treat benign lesions of the skin; nPulse Vybrance Percutaneous Electrode system for soft tissue ablation in surgical setting; nPulse Cardiac Surgical Clamp designed for use in surgical treatment of atrial fibrillation (AF); nPulse Cardiac Catheter System designed to provide a circumferential, or circular, ablation in a single treatment cycle; and nPulse Console, a software-enabled console-based platform designed to accommodate the clinical workflow preferred by physicians. The company was formerly known as Electroblate, Inc. and changed its name to Pulse Biosciences, Inc. in December 2015. Pulse Biosciences, Inc. was incorporated in 2014 and is headquartered in Miami, Florida.

Moat Signals

Competitive analysis based on 41 quarters of fundamental data

Pricing Power

Weak Moat

Operating margins are under pressure, averaging -1049516921.5%. The business may lack pricing power or face rising costs.'

Competitive Advantage

Weak Moat

ROE is low or negative, suggesting limited competitive advantage or capital allocation challenges.

Risk Signals

Data-driven red flags and warnings across 41 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Leverage Risk

Healthy

Limited debt-to-equity data available.

Revenue Decline

Healthy

Revenue is stable or growing over recent quarters — demand appears durable.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 18.9% — significant dilution, likely from stock compensation or capital raises.

Metrics at a Glance

as of March 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$751,000
3Q
Q. Revenue
$401,000
3Q
TTM EBITDA
$-77.00M
23%
TTM Op. Income
$-78.05M
23%
Q. Op. Income
$-19.15M
6%
TTM Net Income
$-74.57M
24%
Q. Net Income
$-18.58M
11%
EPS
$-0.27
8%
Shares Out.
$67.99M
5Q
$751,000 in TTM revenue grew Infinity% YoY, reaching $401,000 last quarter. TTM EBITDA of $-77.00M and TTM operating income of $-78.05M shows growth is flowing through. However, net income is negative at $74.57M — growth is not yet reaching the bottom line. Revenue is growing at a healthy pace — a signal to hold. Across the last 8 quarters, TTM revenue has risen for 3 consecutive quarters — a improving trend.

Margins

Gross, EBITDA, operating, and net margin trends

Gross Margin
7.7%
2Q
EBITDA Margin
-4712.0%
2Q
Op. Margin
-4775.6%
3Q
Net Margin
-4633.7%
3Q
Op. margin of -4775.6% is up 1804395224.4% YoY — cost efficiency is improving. Net margin at -4633.7% and gross margin of 7.7% — earnings take a bigger bite when COGS stays lean.. Across the last 8 quarters, Operating margin has risen for 3 consecutive quarters — a improving trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
3416.0x
P/B Ratio
38.7x
324%
P/S of 3416.0x and P/B of 38.7x. A high P/S suggests growth expectations are priced in.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$81.62M
4Q
Cash
$68.32M
4Q
Long-Term Debt
N/A
Book Value
$66.30M
4Q
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-14.60M
8%
TTM Free Cash Flow
$-55.50M
6Q
FCF Margin
-7390.0%
2Q
FCF / Net Income
0.7
11%
TTM FCF of $-55.50M on $-14.60M in operating cash flow. The FCF / Net Income ratio of 0.7x means earnings are well backed by actual cash — high-quality earnings. Across the last 8 quarters, Free cash flow has fallen for 6 consecutive quarters — a deteriorating trend.

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Cash Generation

Weak Moat

Only 0 of the last 8 quarters had positive FCF — the business may require external capital to sustain operations.

Demand Durability

Weak Moat

Revenue has been flat or declining over recent quarters, which may indicate eroding demand or competitive pressure.