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Oric Pharmaceuticals (ORIC) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Oric Pharmaceuticals
NasdaqGS•Healthcare•Biotechnology
$12.62-0.24(-0.02%)Pre-market
Market Cap
$1.35B
P/B
3.6x

ORIC Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of therapies to counter the resistance mechanisms in cancers in the United States. Its clinical stage product candidates include enozertinib formerly known as ORIC-114, a brain penetrant orally bioavailable irreversible inhibitor, currently under Phase 1b study, that selectively target epidermal growth factor receptor (EGFR) exon 20 and human epidermal growth factor receptor 2 exon 20 with high potency towards exon 20 insertion mutations; and rinzimetostat formerly known as ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 for prostate cancer, currently under Phase 1b study. It has a clinical trial collaboration and supply agreement with Bayer to evaluate ORIC-944 in combination with Nubeqa AR inhibitor; and a clinical trial collaboration and supply agreement with Johnson & Johnson to evaluate ORIC 944 in combination with Erleada AR inhibitor. The company was incorporated in 2014 and is headquartered in South San Francisco, California.

D

How this company scores

WeakMetricSide Score: 31/100

Strongest: Balance Sheet & Red Flags (15/25); weakest: Profitability (2/25).

Profitability2/25
Growth6/25
Balance Sheet & Red Flags15/25
Cash & Earnings Quality8/25
Strengths
Interest easily coveredNet cash position

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/B · 3.6x5y range 0.6x – 3.6x
P/B 3.6x · above its 20-quarter median

Currently above its 20-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $1.35B

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-154.40M
2Q
TTM Op. Income
$-156.14M
2Q
Q. Op. Income
$-45.30M
2Q
TTM Net Income
$-140.35M
2Q
Q. Net Income
$-41.49M
2Q
EPS
$-0.38
19%
Shares Out.
$108.01M
2Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-154.40M and TTM operating income of $-156.14M show growth is flowing through to the bottom line. However, net income is negative at $140.35M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-4529600000.0%
2Q
Net Margin
-4149200000.0%
2Q
Op. margin of -4529600000.0% is down 623200000.0% YoY — costs are rising relative to revenue. Net margin at -4149200000.0% Across the last 8 quarters, operating margin has fallen for 2 consecutive quarters — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
P/B Ratio
3.6x
2Q
P/S of 0.0x and P/B of 3.6x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$404.69M
17%
Cash
$37.48M
51%
Long-Term Debt
N/A
Book Value
$381.26M
18%
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-31.61M
2%
TTM Free Cash Flow
$-112.26M
7%
FCF Margin
N/A
FCF / Net Income
0.8
4Q
TTM FCF of $-112.26M on $-31.61M in operating cash flow. The FCF / Net Income ratio of 0.8x means free cash flow covers net income — earnings are backed by cash. Over the past year, free cash flow is up 7% — a weakening trend.

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Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 53.1% — significant dilution, likely from stock compensation or capital raises.