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Nuvation Bio (NUVB) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Nuvation Bio
NYSE•Healthcare•Biotechnology
$5.78-0.02(<0.01%)Pre-market
Market Cap
$2.12M
P/S
0.0x
P/B
0.0x

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.

C

How this company scores

AverageMetricSide Score: 57/100

Strongest: Growth (20/25); weakest: Cash & Earnings Quality (9/25).

Profitability14/25
Growth20/25
Balance Sheet & Red Flags14/25
Cash & Earnings Quality9/25
Strengths
Growing revenueLong cash runwayProfit converts from growthConsistent growth

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/S · 0.0x5y range 0.0x – 0.5x
P/S 0.0x · below its 9-quarter median

Currently below its 9-quarter median.

P/B · 0.0x5y range 0.0x – 0.0x
P/B 0.0x · above its 17-quarter median

Currently above its 17-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 7 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $2.12M

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$169.90M
7Q
Q. Revenue
$31.69M
556%
TTM EBITDA
$-137.63M
3Q
TTM Op. Income
$-137.63M
3Q
Q. Op. Income
$-51.04M
20%
TTM Net Income
$-149.83M
26%
Q. Net Income
$-62.84M
6%
EPS
$-0.18
6%
Shares Out.
$348,770
6Q
$169.90M in TTM revenue grew 1083.6% YoY, reaching $31.69M last quarter. TTM EBITDA of $-137.63M and TTM operating income of $-137.63M show growth is flowing through to the bottom line. However, net income is negative at $149.83M — growth is not yet reaching the bottom line. Across the last 8 quarters, TTM revenue has risen for 7 consecutive quarters — an improving trend.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
-161.1%
88%
Op. Margin
-161.1%
88%
Net Margin
-198.3%
84%
Op. margin of -161.1% is up 1154.7% YoY — cost efficiency is improving. Net margin at -198.3% Over the past year, operating margin is up 88% — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
0.0x
73%
P/B Ratio
0.0x
368%
P/S of 0.0x and P/B of 0.0x. P/S is low relative to typical market levels.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$744.50M
2Q
Cash
$258.60M
4%
Long-Term Debt
$242.62M
4Q
Book Value
$253.86M
32%
D/E Ratio
1.0
659%
Debt/EBITDA
N/A
With $744.50M in assets and $242.62M in long-term debt, D/E is 1.0and book value is $253.86M — a conservative capital structure with a cushion to weather downturns. Over the past year, debt/equity is up 659% — a weakening trend.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-42.97M
11%
TTM Free Cash Flow
$-128.52M
3Q
FCF Margin
-75.6%
7Q
FCF / Net Income
0.9
3%
TTM FCF of $-128.52M on $-42.97M in operating cash flow. The FCF / Net Income ratio of 0.9x means free cash flow covers net income — earnings are backed by cash. Across the last 8 quarters, free cash flow has risen for 3 consecutive quarters — an improving trend.

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Leverage Risk

Watch

Debt-to-equity has risen 658.7% recently — increasing financial risk even if the current ratio is manageable.

Cash Burn

Red Flag

The last 6 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 27.5% — significant dilution, likely from stock compensation or capital raises.