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Neurogene (NGNE) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Neurogene
NasdaqGM•Healthcare•Biotechnology
$35.48-0.64(-0.02%)Market closed
Market Cap
$730.91M
P/B
3.4x

Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease. It has a license agreement with The University of Edinburgh, Virovek, Inc., Sigma-Aldrich Co. LLC., and Leland Stanford Junior University. The company was founded in 2018 and is headquartered in New York, New York.

D

How this company scores

WeakMetricSide Score: 33/100

Strongest: Balance Sheet & Red Flags (15/25); weakest: Cash & Earnings Quality (6/25).

Profitability6/25
Growth6/25
Balance Sheet & Red Flags15/25
Cash & Earnings Quality6/25
Strengths
Interest easily coveredNet cash position

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/S · 265.8x5y range 265.8x – 769.0x
P/S 265.8x · below its 4-quarter median

Currently below its 4-quarter median.

P/B · 3.4x5y range 0.8x – 51.4x
P/B 3.4x · below its 19-quarter median

Currently below its 19-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $730.91M

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-118.19M
6Q
TTM Op. Income
$-121.35M
6Q
Q. Op. Income
$-36.67M
3Q
TTM Net Income
$-111.11M
7Q
Q. Net Income
$-34.49M
3Q
EPS
$-1.53
3Q
Shares Out.
$22.55M
7Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-118.19M and TTM operating income of $-121.35M show growth is flowing through to the bottom line. However, net income is negative at $111.11M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-3667000000.0%
3Q
Net Margin
-3448800000.0%
3Q
Op. margin of -3667000000.0% is down 1058900000.0% YoY — costs are rising relative to revenue. Net margin at -3448800000.0% Across the last 8 quarters, operating margin has fallen for 3 consecutive quarters — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
2Q
P/B Ratio
3.4x
192%
P/S of 0.0x and P/B of 3.4x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$244.36M
2Q
Cash
$112.48M
91%
Long-Term Debt
N/A
Book Value
$217.13M
6Q
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-23.76M
22%
TTM Free Cash Flow
$-87.71M
2Q
FCF Margin
N/A
2Q
FCF / Net Income
0.8
3Q
TTM FCF of $-87.71M on $-23.76M in operating cash flow. The FCF / Net Income ratio of 0.8x means free cash flow covers net income — earnings are backed by cash. Across the last 8 quarters, free cash flow has fallen for 2 consecutive quarters — a weakening trend.

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Revenue Decline

Red Flag

TTM revenue has contracted 100.0% — significant decline indicating deteriorating demand.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 33.0% — significant dilution, likely from stock compensation or capital raises.