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Mineralys Therapeutics (MLYS) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Mineralys Therapeutics
NasdaqGS•Healthcare•Biotechnology
$27.54-1.37(-0.05%)Pre-market
Market Cap
$2.37B
P/B
4.3x

Mineralys Therapeutics, Inc., a biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States. It is developing lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor for the treatment of cardiorenal conditions affected by dysregulated aldosterone, such as hypertension, chronic kidney disease, and obstructive sleep apnea. The company was formerly known as Catalys SC1, Inc. and changed its name to Mineralys Therapeutics, Inc. in May 2020. Mineralys Therapeutics, Inc. was incorporated in 2019 and is headquartered in Radnor, Pennsylvania.

D

How this company scores

WeakMetricSide Score: 33/100

Strongest: Balance Sheet & Red Flags (15/25); weakest: Profitability (4/25).

Profitability4/25
Growth6/25
Balance Sheet & Red Flags15/25
Cash & Earnings Quality8/25
Strengths
Interest easily coveredNet cash position

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/B · 4.3x5y range 1.3x – 4.8x
P/B 4.3x · above its 14-quarter median

Currently above its 14-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $2.37B

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-370.75M
2Q
TTM Op. Income
$-370.79M
2Q
Q. Op. Income
$-246.04M
2Q
TTM Net Income
$-349.58M
83%
Q. Net Income
$-241.07M
2Q
EPS
$-2.85
332%
Shares Out.
$84.73M
2Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-370.75M and TTM operating income of $-370.79M show growth is flowing through to the bottom line. However, net income is negative at $349.58M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-24604000000.0%
2Q
Net Margin
-24107100000.0%
2Q
Op. margin of -24604000000.0% is down 19929400000.0% YoY — costs are rising relative to revenue. Net margin at -24107100000.0% Across the last 8 quarters, operating margin has fallen for 2 consecutive quarters — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
P/B Ratio
4.3x
53%
P/S of 0.0x and P/B of 4.3x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$667.85M
99%
Cash
$138.27M
36%
Long-Term Debt
N/A
Book Value
$550.92M
2Q
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-32.56M
8%
TTM Free Cash Flow
$-138.80M
28%
FCF Margin
N/A
FCF / Net Income
0.4
5Q
TTM FCF of $-138.80M on $-32.56M in operating cash flow. The FCF / Net Income ratio of 0.4x means cash covers only part of net income — earnings quality needs attention. Over the past year, free cash flow is up 28% — a weakening trend.

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Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 70.1% — significant dilution, likely from stock compensation or capital raises.