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MBX Biosciences (MBX) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

MBX Biosciences
NasdaqGS•Healthcare•Biotechnology
$62.91-0.98(-0.02%)Market closed
Market Cap
$3.00B
P/B
7.3x

MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is Canvuparatide (MBX 2109), a parathyroid hormone peptide prodrug, which is in Phase 3 clinical trial for the treatment of chronic hypoparathyroidism. The company is also developing Imapextide (MBX 1416), a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 2 clinical trial a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies for the treatment of obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana.

D

How this company scores

WeakMetricSide Score: 39/100

Strongest: Balance Sheet & Red Flags (15/25); weakest: Growth (6/25).

Profitability10/25
Growth6/25
Balance Sheet & Red Flags15/25
Cash & Earnings Quality8/25
Strengths
Interest easily coveredProfit converts from growthNet cash position

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/B · 7.3x5y range 0.6x – 7.3x
P/B 7.3x · above its 8-quarter median

Currently above its 8-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $3.00B

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-117.68M
2Q
TTM Op. Income
$-117.92M
2Q
Q. Op. Income
$-40.93M
4Q
TTM Net Income
$-104.29M
1%
Q. Net Income
$-37.09M
4Q
EPS
$-0.78
34%
Shares Out.
$47.70M
7Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-117.68M and TTM operating income of $-117.92M show growth is flowing through to the bottom line. However, net income is negative at $104.29M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-4093100000.0%
4Q
Net Margin
-3709500000.0%
4Q
Op. margin of -4093100000.0% is down 1912600000.0% YoY — costs are rising relative to revenue. Net margin at -3709500000.0% Across the last 8 quarters, operating margin has fallen for 4 consecutive quarters — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
P/B Ratio
7.3x
321%
P/S of 0.0x and P/B of 7.3x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$435.91M
88%
Cash
$54.12M
36%
Long-Term Debt
N/A
Book Value
$409.54M
87%
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-22.62M
2Q
TTM Free Cash Flow
$-85.20M
12%
FCF Margin
N/A
FCF / Net Income
0.8
2Q
TTM FCF of $-85.20M on $-22.62M in operating cash flow. The FCF / Net Income ratio of 0.8x means free cash flow covers net income — earnings are backed by cash. Over the past year, free cash flow is up 12% — a weakening trend.

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Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 632.0% — significant dilution, likely from stock compensation or capital raises.