MetricSide LogoMetricSide
Learn
  1. Home
  2. Companies
  3. Healthcare
  4. INSM
OverviewMetricsPricesRevenue & ProfitAssets & LiabilitiesCash FlowMarginsPrice RatiosOthers
MetricSide

Standardized stock fundamentals and valuation metrics. Analyze revenue, EBITDA, free cash flow, and more with interactive charts.

Stock Sectors

  • Technology
  • Healthcare
  • Financials
  • Consumer
  • Industrials
  • Energy
  • Real Estate
  • Materials

Legal & Contact

  • Terms of Service
  • Privacy Policy
  • Contact Us
Not Financial Advice: MetricSide is a data aggregation and visualization tool. Nothing on this website constitutes investment advice, a recommendation, or a solicitation to buy or sell any security. All data is provided for informational and educational purposes only. Past performance is not indicative of future results. Always consult a qualified financial professional before making investment decisions. Data accuracy is not guaranteed — verify critical information against official sources.

© 2026 MetricSide. All rights reserved.

Insmed Incorporated (INSM) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Insmed Incorporated
NasdaqGS•Healthcare•Biotechnology
$93.39-1.67(-0.02%)Pre-market
Market Cap
$23.92B
P/S
15.7x
P/B
32.9x

Insmed Incorporated develops and commercializes therapies for patients with serious and rare diseases in the United States, Europe, Japan, and internationally. The company offers ARIKAYCE for the treatment of refractory nontuberculous mycobacterial lung infections, as well as is in phase 3 clinical trial for the treatment of mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients. It also develops brensocatib, an oral reversible inhibitor of dipeptidyl peptidase 1(DPP1) that is in phase 3 clinical trial for the treatment of bronchiectasis; and in phase 2 clinical trial for the treatment of chronic rhinosinusitis without nasal polyps and hidradenitis suppurativa. In addition, the company is developing treprostinil palmitil inhalation powder, an inhaled formulation of a treprostinil prodrug treprostinil palmitil, which is in phase 3 clinical trial for the treatment of pulmonary hypertension associated with interstitial lung disease; and phase 2 clinical trial for the treatment of pulmonary arterial hypertension. Further, it develops INS1201, a microdystrophin adeno-associated virus gene replacement therapy which is in phase 1 clinical trial for the treatment of Duchenne muscular dystrophy, as well as it is also developing pre-clinical research programs for gene therapy, AI-driven protein engineering, protein manufacturing, RNA end-joining, and synthetic rescue. In addition, it provides INS1148, monoclonal antibody targeting stem cell factor called SCF248 that is in phase-2 clinical trial for the treatment of interstitial lung disease, and asthma; and INS1202, an intrathecally delivered gene therapy which is in phase 1 of clinical trial for the treatment of amyotrophic lateral sclerosis. The company was founded in 1988 and is headquartered in Bridgewater, New Jersey.

C

How this company scores

AverageMetricSide Score: 50/100

Strongest: Growth (20/25); weakest: Cash & Earnings Quality (8/25).

Profitability10/25
Growth20/25
Balance Sheet & Red Flags12/25
Cash & Earnings Quality8/25
Strengths
Growing revenueProfit converts from growthConsistent growth

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/S · 15.7x5y range 15.7x – 67.1x
P/S 15.7x · below its 20-quarter median

Currently below its 20-quarter median.

P/B · 32.9x5y range 15.2x – 271.4x
P/B 32.9x · below its 14-quarter median

Currently below its 14-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $23.92B

Metrics at a Glance

as of September 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$1.52B
7Q
Q. Revenue
$524.43M
6Q
TTM EBITDA
$-563.99M
3Q
TTM Op. Income
$-563.99M
3Q
Q. Op. Income
$-89.37M
76%
TTM Net Income
$-605.61M
3Q
Q. Net Income
$-100.32M
73%
EPS
$-0.46
74%
Shares Out.
$218.79M
7Q
$1.52B in TTM revenue grew 240.0% YoY, reaching $524.43M last quarter. TTM EBITDA of $-563.99M and TTM operating income of $-563.99M show growth is flowing through to the bottom line. However, net income is negative at $605.61M — growth is not yet reaching the bottom line. Across the last 8 quarters, TTM revenue has risen for 7 consecutive quarters — an improving trend.

Margins

Gross, EBITDA, operating, and net margin trends

Gross Margin
85.1%
7%
EBITDA Margin
-17.0%
93%
Op. Margin
-17.0%
93%
Net Margin
-19.1%
93%
Op. margin of -17.0% is up 240.1% YoY — cost efficiency is improving. Net margin at -19.1% and gross margin of 85.1% show how much of each revenue dollar survives to profit. Over the past year, operating margin is up 93% — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
15.7x
4Q
P/B Ratio
32.9x
4%
P/S of 15.7x and P/B of 32.9x. P/S is high, meaning growth expectations are priced in.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$2.23B
2Q
Cash
$396.56M
2Q
Long-Term Debt
$544.86M
5Q
Book Value
$726.21M
23%
D/E Ratio
0.8
31%
Debt/EBITDA
N/A
With $2.23B in assets and $544.86M in long-term debt, D/E is 0.8and book value is $726.21M — a conservative capital structure with a cushion to weather downturns. Over the past year, debt/equity is up 31% — a weakening trend.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-36.46M
3Q
TTM Free Cash Flow
$-627.58M
3Q
FCF Margin
-41.3%
5Q
FCF / Net Income
1.0
3Q
TTM FCF of $-627.58M on $-36.46M in operating cash flow. The FCF / Net Income ratio of 1.0x means free cash flow covers net income — earnings are backed by cash. Across the last 8 quarters, free cash flow has risen for 3 consecutive quarters — an improving trend.

Related Stocks in Healthcare

View Sector
LLY$938.28B
Lilly (Eli)
Drug Manufacturers - General
JNJ$586.47B
Johnson & Johnson
Drug Manufacturers - General
ABBV$411.57B
AbbVie
Drug Manufacturers - General
MRK$303.29B
Merck & Co.
Drug Manufacturers - General
UNH$249.74B
UnitedHealth Group
Healthcare Plans
TMO$203.77B
Thermo Fisher Scientific
Diagnostics & Research
AMGN$201.34B
Amgen
Drug Manufacturers - General
GILD$191.61B
Gilead Sciences
Drug Manufacturers - General

Leverage Risk

Watch

Debt-to-equity has risen 31.4% recently — increasing financial risk even if the current ratio is manageable.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 22.0% — significant dilution, likely from stock compensation or capital raises.