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Definium Therapeutics (DFTX) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Definium Therapeutics
NasdaqGS•Healthcare•Biotechnology
$37.85+1.03(0.03%)Pre-market
Market Cap
$4.30B
P/B
4.7x

Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder. The company was formerly known as Mind Medicine (MindMed) Inc. and changed its name to Definium Therapeutics, Inc. in January 2026. Definium Therapeutics, Inc. is headquartered in New York, New York.

C

How this company scores

AverageMetricSide Score: 41/100

Strongest: Balance Sheet & Red Flags (21/25); weakest: Cash & Earnings Quality (6/25).

Profitability8/25
Growth6/25
Balance Sheet & Red Flags21/25
Cash & Earnings Quality6/25
Strengths
Long cash runwayLow leverageImproving leverageNet cash position

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/B · 4.7x5y range 0.4x – 7.9x
P/B 4.7x · above its 19-quarter median

Currently above its 19-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $4.30B

Metrics at a Glance

as of June 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-227.54M
7Q
TTM Op. Income
$-227.54M
7Q
Q. Op. Income
$-75.08M
5Q
TTM Net Income
$-353.79M
5Q
Q. Net Income
$-158.99M
2Q
EPS
$-1.44
188%
Shares Out.
$110.68M
6Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-227.54M and TTM operating income of $-227.54M show growth is flowing through to the bottom line. However, net income is negative at $353.79M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-7507700000.0%
5Q
Net Margin
-15898600000.0%
2Q
Op. margin of -7507700000.0% is down 3417400000.0% YoY — costs are rising relative to revenue. Net margin at -15898600000.0% Across the last 8 quarters, operating margin has fallen for 5 consecutive quarters — a weakening trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
P/B Ratio
4.7x
57%
P/S of 0.0x and P/B of 4.7x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$1.11B
320%
Cash
$655.27M
3Q
Long-Term Debt
$36.47M
11%
Book Value
$918.68M
396%
D/E Ratio
0.0
82%
Debt/EBITDA
N/A
With $1.11B in assets and $36.47M in long-term debt, D/E is 0.0and book value is $918.68M — a conservative capital structure with a cushion to weather downturns. Over the past year, debt/equity is down 82% — an improving trend.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-52.78M
78%
TTM Free Cash Flow
$-167.95M
7Q
FCF Margin
N/A
FCF / Net Income
0.5
2Q
TTM FCF of $-167.95M on $-52.78M in operating cash flow. The FCF / Net Income ratio of 0.5x means cash covers only part of net income — earnings quality needs attention. Across the last 8 quarters, free cash flow has fallen for 7 consecutive quarters — a weakening trend.

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Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 42.1% — significant dilution, likely from stock compensation or capital raises.