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Acumen Pharmaceuticals (ABOS) Stock Fundamentals, Analysis & Risk Signals

Health score, price, valuation, risk signals, and key metrics at a glance.

Acumen Pharmaceuticals
NasdaqGS•Healthcare•Biotechnology
$1.98-0.08(-0.04%)Market closed
Market Cap
$16.23M
P/B
0.5x

Acumen Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops targeted therapies for the treatment of Alzheimer's disease. It focuses on advancing a targeted immunotherapy drug candidate, sabirnetug (ACU193), which is in its Phase 2 ALTITUDE-AD clinical trial to target toxic soluble amyloid beta oligomers. Acumen Pharmaceuticals, Inc. has a collaboration and license agreement with Halozyme, Inc. for the development of a subcutaneous formulation of Sabirnetug, as well as with JCR Pharmaceuticals Co. Ltd for the development of Aß oligomer-targeted enhanced brain delivery therapy for the treatment of Alzheimer's disease. The company was incorporated in 1996 and is headquartered in Newton, Massachusetts.

D

How this company scores

WeakMetricSide Score: 44/100

Grade capped at D — Interest coverage below 1× (-26.2x) — earnings cannot cover interest. Strongest: Balance Sheet & Red Flags (17/25); weakest: Growth (6/25).

Profitability13/25
Growth6/25
Balance Sheet & Red Flags17/25
Cash & Earnings Quality8/25
Strengths
Low leverageProfit converts from growthImproving leverageNet cash position
Grade capped at D
  • Interest coverage below 1× (-26.2x) — earnings cannot cover interest.

Valuation vs. 5-year range

Today's multiple positioned against its own trailing range — a visual premium/discount check.

P/B · 0.5x5y range 0.4x – 3.5x
P/B 0.5x · below its 20-quarter median

Currently below its 20-quarter median.

Watch items

Data-driven signals worth keeping an eye on across the last 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Price & Volume
Market Cap $16.23M

Metrics at a Glance

as of September 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$0
Q. Revenue
$0
TTM EBITDA
$-104.64M
5Q
TTM Op. Income
$-104.72M
5Q
Q. Op. Income
$-25.81M
3%
TTM Net Income
$-103.96M
5Q
Q. Net Income
$-25.37M
4%
EPS
$-0.35
20%
Shares Out.
$72.32M
4Q
$0 in TTM revenue was flat at zero YoY, reaching $0 last quarter. TTM EBITDA of $-104.64M and TTM operating income of $-104.72M show growth is flowing through to the bottom line. However, net income is negative at $103.96M — growth is not yet reaching the bottom line.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
N/A
Op. Margin
-2581300000.0%
3%
Net Margin
-2536900000.0%
4%
Op. margin of -2581300000.0% is up 70000000.0% YoY — cost efficiency is improving. Net margin at -2536900000.0% Over the past year, operating margin is up 3% — an improving trend.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
N/A
P/B Ratio
0.5x
54%
P/S of 0.0x and P/B of 0.5x.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$85.56M
2Q
Cash
$53.08M
13%
Long-Term Debt
$5.87M
5Q
Book Value
$34.61M
2Q
D/E Ratio
0.2
42%
Debt/EBITDA
N/A
With $85.56M in assets and $5.87M in long-term debt, D/E is 0.2and book value is $34.61M — a conservative capital structure with a cushion to weather downturns. Over the past year, debt/equity is down 42% — an improving trend.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-26.65M
13%
TTM Free Cash Flow
$-87.95M
4Q
FCF Margin
N/A
FCF / Net Income
0.8
3Q
TTM FCF of $-87.95M on $-26.65M in operating cash flow. The FCF / Net Income ratio of 0.8x means free cash flow covers net income — earnings are backed by cash. Across the last 8 quarters, free cash flow has risen for 4 consecutive quarters — an improving trend.

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Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 20.4% — significant dilution, likely from stock compensation or capital raises.